Yes, holy and also when testosterone usually undergoes an initial spike in serum levels. Granted it gets better and better the longer you go. 21 days is also a very auspicious or 'holy' number if you will.
For instance I am Buddhist, and monks and even my Dharma bros and I will recite The Great Compassion Mantra 7 to 21 times in a row. 49 is also an auspicious number. 108 is even more auspicious, an extremely holy number if you will. I have bowed 108 times to the Ksitigharba Sutra for instance, many Zen practioners will bow 108 times a day at their altar as part of their daily practice.