https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-019-0406-z#:~:text=Blocking%20androgen%20receptors%20can%20decreases%20the%20expression%20of,energy%20efficiency%20and%20fat%20metabolism%20by%20suppressing%20CPTI.
Mice have a very similar biology to humans (reason...
https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-019-0406-z
To put simply:
PMO > nullified androgen receptors > little to no T uptake > carnitine not present in skeletal muscle > fatty acids cannot be used as energy.
Low T to E ratio is also bad for fat loss.
There's...