(I'm assuming the covid vaccine) The vaccine itself, no there hasn't really been a link to sexual health or anything like that. Only thing I could see, which is a huuuuuge stretch, is that the fatigue and other side effects you could get may encourage you to pmo on that one day to distract from the feeling? But that's just one or two days if you get two doses, so I wouldn't sweat it if that's the only thing you're considering with the vaccine.